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KMID : 0387419940050010093
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Korean Society of Oriental Neuropsychiatry
1994 Volume.5 No. 1 p.93 ~ p.101
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The Effects of Galgunhaejutang + Danjuhwan and Haejujigaltang on the Experimental Behaviors of Alcohol-Intoxicated Mice
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Abstract
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This experiment was designed to investigate the effects of Galgunhaeiutang + Danjuhwan and Haejujigaltang on the experimental behaviors of alcohol-inticxicated mice.
ICR mice were used as subjects for alcohol intoxication in this experiment and sample group received Herb Medicine. The foot-step and rearing score were measured in mice. Also Rota-Rod treadmill & number of successful trials swimming time in the T-maze were done. And the following results were observed;
1. The food-step score was decreased in Galgunhaejutang + Danjuhwan group at the 8th hour, the difference was statistically significant. But Haejujigaltang group showed no significant difference.
2. The number of rearing was decreased in Galgunhaejutang + Danjuhwan group at the 3rd and 8th hour, the difference was statistical significant, while Haejujigaltang group showed no significant differnce.
3. The motor incoordination measered by the Rota-Rod treadmill was decreased in Galgunhaejutang + Danjuhwan group at the 8th hour, but Haejujigaltang group showed no significant difference.
4. The number of successful trials in T-maze showed no significant difference in both groups.
5. The passing time in T-maze was increased in Galgunhaejutang +Danjuhwan group at the 8th hour, but Haejujigaltang group showed no significant difference.
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